|
KMID : 0390220130240020225
|
|
Journal of Clinical Otolaryngology, Head and Neck Surgery
2013 Volume.24 No. 2 p.225 ~ p.232
|
|
|
Sensorineural Hearing Loss Corrected by Thiamine Supply : A Case Report
|
|
Lim Hyun-Gon
Kim Min-Bum
Choi Ho-Seok
Kim Kyu-Sung
|
|
|
Abstract
|
|
|
|
Wernicke encephalopathy is a severe neurological disorder caused by thiamine (vitamin B1) deficiency. This disease occurs mostly in alcoholics due to malnutrition or malabsorption of vitamin B1 but also occurs in hyperemesis gravidarum, carcinoma, anorexia nervosa. Auditory neuropathy is characterized by abnormal auditory brainstem and preserved cochlear outer hair cell function. This is a case of Auditory neuropathy caused by thiamine deficiency. Brain MRI scan showed typical Wernicke encephalopathy finding. To evaluate hearing impairment, Pure tone audiogram, Speech audiogram, Otoacoustic emision and Auditory brainstem evoked response were measured and the result were compatible with auditory neuropathy. After thiamine replacement therapy, patient’s hearing imparment and serial speech recognition score showed improvement. From our study, we can assume that thiamine deficiency cause selective destruction of inner ear cell, this will eventually helps us to reveal pathophysiolology of auditory neuropathy.
|
|
|
KEYWORD
|
|
|
Thiamine deficiency, Sensorineural hearing loss, Wernicke encephalopathy, Auditory brainstem eovked response, Otoacoustic emissions
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|